Faculty of Natural
Sciences
Comenius University in Bratislava

LABORATORY OF FUNCTIONAL AND COMPARATIVE GENOMICS

Link to own page: www.biocenter.sk/welcome1.html

Joint Department of the Department of Biochemistry and Department of Genetics

Link to Department of Genetics : http://www.fns.uniba.sk/kge/

Our ambition is to understand the nature of complex biological phenomena. We analyze the genomes of non-conventional yeast species (Candida, Magnusiomyces, Saprochaete, Schizosaccharomyces, Yarrowia). Our goal is to uncover the functions of conserved as well as species-specific genes and their interactions. In our studies, we combine approaches of biochemistry, bioinformatics, genetics, genomics, cell and molecular biology. Specifically, we investigate (i) the structure, function and evolution of chromosomal telomeres, (ii) the molecular architecture of mitochondrial genomes and the expression of mitochondrial genes, (iii) the functions of metabolic gene clusters, (iv) the evolution of biochemical pathways, and (v) the biogenesis of mitochondria and vacuoles in eukaryotic cells.