Faculty of Natural
Comenius University Bratislava


Mitochondria are essential organelles of eukaryotic cells. Their basic functions include the production of ATP in the oxidative phosphorylation process, as well as the regulation of cell survival as they are involved in regulating programmed cell death. Both of these processes are strictly dependent on the selective permeability of the mitochondrial membranes. In our laboratory, we use Saccharomyces cerevisiae, as well as a number of non-traditional yeasts as a model organism for the study of adenine nucleotide transport (ATP, ADP) across mitochondrial membranes, and to study changes in the permeability of mitochondrial membranes through proteins regulating programmed cell death.